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Assay Detail

CHEMBL747259

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested in vitro for N-methyl-D-aspartate glutamate receptor binding using [3H]L-glutamate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Glutamate NMDA receptor (CHEMBL1907608)
Type PROTEIN COMPLEX GROUP
Organism Rattus norvegicus

Publication

Synthesis and biological evaluation of cyclopropyl analogues of 2-amino-5-phosphonopentanoic acid.
Dappen MS, Pellicciari R, Natalini B, Monahan JB, Chiorri C, Cordi AA.
J Med Chem (1991) 34 : 161 -168
PubMed 1671413 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.38 6.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL28862 1 6.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL28862 Ki = 420.0 nM 6.38