Assay Detail
ADMET
CHEMBL747315
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Cytotoxicity of compound against human normal neonatal foreskin fibroblasts (NFF) cell line
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | NFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiproliferative and phenotype-transforming antitumor agents derived from cysteine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.19 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL318384 | — | — | 1 | 6.46 |
| CHEMBL101006 | — | — | 1 | 6.10 |
| CHEMBL103508 | — | — | 1 | 6.10 |
| CHEMBL103379 | — | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL318384 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL101006 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL103508 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL103379 | — | IC50 | = | 830.0 | nM | 6.08 |