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Assay Detail

CHEMBL747471

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for binding activity against muscarinic acetylcholine receptor M3, using [3H]-QNB as the radioligand.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glutathione S-transferase theta-1 (CHEMBL2423)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis, molecular modeling studies, and muscarinic receptor activity of azaprophen analogues.
Triggle DJ, Kwon YW, Abraham P, Pitner JB, Mascarella SW, Carroll FI.
J Med Chem (1991) 34 : 3164 -3171
PubMed 1956033 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.17 9.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL321214 1 9.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL321214 Ki = 0.68 nM 9.17