Assay Detail
Functional
CHEMBL747660
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibition of [3H]pirenzepine binding against Muscarinic acetylcholine receptor M1 from rat cortical membranes using in vitro cholinergic receptor binding assay.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Muscarinic acetylcholine receptor M1 (CHEMBL276) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Substituted (pyrroloamino)pyridines: potential agents for the treatment of Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.89 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29835 | BESIPIRDINE | 2.0 | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29835 | BESIPIRDINE | IC50 | = | 1300.0 | nM | 5.89 |