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Assay Detail

CHEMBL747713

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Evaluated for the binding affinity at mu receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mu-type opioid receptor (CHEMBL2858)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Selective kappa-opioid agonists: synthesis and structure-activity relationships of piperidines incorporating on oxo-containing acyl group.
Giardina G, Clarke GD, Dondio G, Petrone G, Sbacchi M, Vecchietti V.
J Med Chem (1994) 37 : 3482 -3491
PubMed 7932577 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.17 5.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL119524 1 5.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL119524 Ki = 6790.0 nM 5.17