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Assay Detail

CHEMBL747772

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards human muscarinic receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Muscarinic acetylcholine receptor M4 (CHEMBL1821)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective optimization of side activities: another way for drug discovery.
Wermuth CG.
J Med Chem (2004) 47 : 1303 -1314
PubMed 14998318 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.26 6.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL285802 ZOTEPINE 2.0 1 6.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL285802 ZOTEPINE Ki = 550.0 nM 6.26