Assay Detail
Binding
CHEMBL747882
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards opioid Mu receptor using [3H]DAMGO as radioligand
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Optically pure (-)-4-[(N-allyl-3-methyl-4-piperidinyl)phenyl-amino]-N,N-diethylbenzami de displays selective binding and full agonist activity for the delta opioid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.18 | 7.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25230 | — | — | 1 | 7.44 |
| CHEMBL115730 | — | — | 1 | 5.92 |
| CHEMBL13470 | SNC-80 | — | 1 | 5.79 |
| CHEMBL102497 | — | — | 1 | 5.58 |
| CHEMBL22650 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25230 | — | Ki | = | 36.0 | nM | 7.44 |
| CHEMBL115730 | — | Ki | = | 1212.0 | nM | 5.92 |
| CHEMBL13470 | SNC-80 | Ki | = | 1614.0 | nM | 5.79 |
| CHEMBL102497 | — | Ki | = | 2623.0 | nM | 5.58 |
| CHEMBL22650 | — | Ki | > | 10000.0 | nM | - |