Assay Detail
Binding
CHEMBL748920
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Inhibitory activity against human N-Myristoyltransferase (NMT).
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Design and syntheses of potent and selective dipeptide inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.69 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34801 | — | — | 1 | 6.64 |
| CHEMBL286570 | — | — | 1 | 6.38 |
| CHEMBL33289 | — | — | 1 | 6.30 |
| CHEMBL54883 | — | — | 1 | 5.94 |
| CHEMBL299249 | — | — | 1 | 4.94 |
| CHEMBL6269 | SC-58272 | — | 1 | 4.85 |
| CHEMBL294596 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34801 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL286570 | — | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL33289 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL54883 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL299249 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL6269 | SC-58272 | IC50 | = | 14100.0 | nM | 4.85 |
| CHEMBL294596 | — | IC50 | = | 16000.0 | nM | 4.80 |