Assay Detail
Binding
CHEMBL749005
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Binding affinity against muscarinic acetylcholine receptor M2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
From hit to lead. Analyzing structure-profile relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.81 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL114379 | — | — | 1 | 6.29 |
| CHEMBL114484 | — | — | 1 | 5.80 |
| CHEMBL115280 | — | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL114379 | — | IC50 | = | 518.0 | nM | 6.29 |
| CHEMBL114484 | — | IC50 | = | 1570.0 | nM | 5.80 |
| CHEMBL115280 | — | IC50 | = | 4540.0 | nM | 5.34 |