Assay Detail
Binding
CHEMBL749191
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The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligand
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Muscarinic acetylcholine receptor (CHEMBL2094109) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.59 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL300647 | — | — | 1 | 8.37 |
| CHEMBL45491 | — | — | 2 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL300647 | — | Ki | = | 4.3 | nM | 8.37 |
| CHEMBL45491 | — | Ki | = | 43.0 | nM | 7.37 |
| CHEMBL45491 | — | Ki | = | 94.0 | nM | 7.03 |