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Assay Detail

CHEMBL749241

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The inhibitory concentration against cultured NIH 3T3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Intermediate

Target

NIH3T3 (CHEMBL614822)
Type CELL-LINE
Organism Mus musculus

Publication

Design and in vivo analysis of potent non-thiol inhibitors of farnesyl protein transferase.
Anthony NJ, Gomez RP, Schaber MD, Mosser SD, Hamilton KA, O'Neil TJ, Koblan KS, Graham SL, Hartman GD, Shah D, Rands E, Kohl NE, Gibbs JB, Oliff AI.
J Med Chem (1999) 42 : 3356 -3368
PubMed 10464022 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL252953 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL252953 IC50 = 10000.0 nM 5.00