Assay Detail
Binding
CHEMBL749276
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Dissociation constant towards Muscarinic acetylcholine receptor was determined by using [3H]4NMPB as radioligand
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Muscarinic acetylcholine receptor (CHEMBL2097162) ↗| Type | PROTEIN FAMILY |
| Organism | Mus musculus |
Publication
N-allyl analogues of phencyclidine: chemical synthesis and pharmacological properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 4.61 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23627 | — | — | 1 | 4.85 |
| CHEMBL23436 | — | — | 1 | 4.82 |
| CHEMBL23626 | — | — | 1 | 4.60 |
| CHEMBL281855 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23627 | — | Kd | = | 14000.0 | nM | 4.85 |
| CHEMBL23436 | — | Kd | = | 15000.0 | nM | 4.82 |
| CHEMBL23626 | — | Kd | = | 25000.0 | nM | 4.60 |
| CHEMBL281855 | — | Kd | = | 70000.0 | nM | 4.16 |