Assay Detail
Functional
CHEMBL749407
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of luminol-dependent chemiluminescence induced by stimulating the neutrophil cells with FMLP (N-formyl-L-methionyl-L-leucyl-l-phenylalanine)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Neutrophil |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.97 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL288758 | — | — | 1 | 6.13 |
| CHEMBL49210 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL288758 | — | IC50 | = | 734.0 | nM | 6.13 |
| CHEMBL49210 | — | IC50 | = | 1599.0 | nM | 5.80 |