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Assay Detail

CHEMBL749470

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration required to stimulate cGMP production in NIE-115 neuroblastoma cells at higher doses in 10-100 uM range
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Synthesis of partially non-peptidic neurotensin mimetics
Dood DS, Kozikowski AP, Cusack B, Richelson E
Bioorg Med Chem Lett (1994) 4 : 1241 -1246
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.72 4.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL21448 1 4.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL21448 EC50 = 19000.0 nM 4.72