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Assay Detail

CHEMBL749662

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for its ability to displace [3H]CPP or [3H]-CGS- 19755 ligand from N-methyl-D-aspartate (NMDA) receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Glutamate NMDA receptor (CHEMBL1907608)
Type PROTEIN COMPLEX GROUP
Organism Rattus norvegicus

Publication

Modeling of competitive phosphono amino acid NMDA receptor antagonists.
Whitten JP, Harrison BL, Weintraub HJ, McDonald IA.
J Med Chem (1992) 35 : 1509 -1514
PubMed 1533680 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL39664 SELFOTEL 2.0 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL39664 SELFOTEL Ki = 130.0 nM 6.89