Assay Detail
Functional
CHEMBL749959
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro antagonist potency in transactivation assay in CV-1 cells expressing androgen receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CV-1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.27 | 7.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL146032 | LONAPRISAN | 2.0 | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL146032 | LONAPRISAN | IC50 | = | 54.0 | nM | 7.27 |