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Assay Detail

CHEMBL750156

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of human erythrocytes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

P2Y purinoceptor 1 (CHEMBL4315)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Purine and pyrimidine (P2) receptors as drug targets.
Jacobson KA, Jarvis MF, Williams M.
J Med Chem (2002) 45 : 4057 -4093
PubMed 12213051 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL69234 1 6.00
CHEMBL336296 URIDINE TRIPHOSPHATE 3.0 1 -
CHEMBL130266 URIDINE_DIPHOSPHATE 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL69234 EC50 = 1000.0 nM 6.00
CHEMBL336296 URIDINE TRIPHOSPHATE EC50 > 100000.0 nM -
CHEMBL130266 URIDINE_DIPHOSPHATE EC50 > 100000.0 nM -