Assay Detail
Binding
CHEMBL750396
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uM
7
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.62 | 8.39 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31421 | — | — | 1 | 8.39 |
| CHEMBL290301 | — | — | 3 | 6.46 |
| CHEMBL340032 | DADLE | — | 1 | 6.35 |
| CHEMBL285250 | — | — | 2 | 6.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31421 | — | IC50 | = | 4.1 | nM | 8.39 |
| CHEMBL290301 | — | IC50 | = | 347.0 | nM | 6.46 |
| CHEMBL290301 | — | IC50 | = | 393.0 | nM | 6.41 |
| CHEMBL340032 | DADLE | IC50 | = | 447.0 | nM | 6.35 |
| CHEMBL285250 | — | IC50 | = | 557.0 | nM | 6.25 |
| CHEMBL290301 | — | IC50 | = | 1388.0 | nM | 5.86 |
| CHEMBL285250 | — | Inhibition | = | 26.0 | % | - |