Assay Detail
Binding
CHEMBL751055
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Evaluated for its affinity towards Opioid receptor mu 1 in rat forebrain by displacing the radioligand [3H]sufentanil.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Dermorphin sequence with high -afinity by fixing the phe sidechain to trans at 1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.29 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278789 | DERMORPHIN | — | 1 | 8.62 |
| CHEMBL25465 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278789 | DERMORPHIN | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL25465 | — | IC50 | = | 11.0 | nM | 7.96 |