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Assay Detail

CHEMBL751074

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against Opioid receptor mu 1 with [3H]CTOP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Mu-type opioid receptor (CHEMBL270)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Topographical requirements for delta opioid ligands: The synthesis and biological properties of a cyclic analogue of deltorphin I
Misicka A, Nikiforovich G, Lipkowski AW, Horvath R, Davis P, Kramer TH, Yamamura HI, Hruby VJ
Bioorg Med Chem Lett (1992) 2 : 547 -552
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.98 8.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL153466 1 8.29
CHEMBL317956 DELTORPHIN C 1 5.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL153466 IC50 = 5.15 nM 8.29
CHEMBL317956 DELTORPHIN C IC50 = 2140.0 nM 5.67