Assay Detail
Binding
CHEMBL751213
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Binding affinity towards guinea pig Opioid receptor mu 1 using radioligand [3H]DAMGO
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
3-Carboxamido analogues of morphine and naltrexone. synthesis and opioid receptor binding properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.44 | 9.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL56585 | CYCLAZOCINE | 2.0 | 1 | 9.49 |
| CHEMBL297428 | — | — | 1 | 9.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL56585 | CYCLAZOCINE | Ki | = | 0.32 | nM | 9.49 |
| CHEMBL297428 | — | Ki | = | 0.41 | nM | 9.39 |