Assay Detail
Binding
CHEMBL751456
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for in vitro inhibition of [3H]-MK-801 at NMDA receptor.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Glutamate NMDA receptor (CHEMBL1907608) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Rattus norvegicus |
Publication
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.85 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL265325 | 1-Aminocyclopropane carboxylic acid | — | 1 | 6.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL265325 | 1-Aminocyclopropane carboxylic acid | EC50 | = | 140.0 | nM | 6.85 |