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Assay Detail

CHEMBL751722

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound with the N-methyl-D-aspartate glutamate receptor blocking activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glutamate receptor ionotropic, NMDA 2C (CHEMBL401)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Emerging molecular approaches to pain therapy.
Williams M, Kowaluk EA, Arneric SP.
J Med Chem (1999) 42 : 1481 -1500
PubMed 10229619 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.16 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL807 MEMANTINE 4.0 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL807 MEMANTINE Ki = 700.0 nM 6.16