Assay Detail
Binding
CHEMBL751725
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of binding of [3H]strychnine to N-methyl-D-aspartate glutamate receptor 1 in rat
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Evaluation and synthesis of aminohydroxyisoxazoles and pyrazoles as potential glycine agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.44 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL66693 | D-ALANINE | — | 1 | 4.77 |
| CHEMBL279597 | ALANINE | 3.0 | 1 | 4.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL66693 | D-ALANINE | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL279597 | ALANINE | IC50 | = | 78000.0 | nM | 4.11 |