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Assay Detail

CHEMBL752035

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Opioid receptor mu 1 of (endomorphin 2) in guinea pig ileum was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Ileum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Mu-type opioid receptor (CHEMBL4354)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Enkephalin analogues with 2',6'-dimethylphenylalanine replacing phenylalanine in position 4.
Sasaki Y, Hirabuki M, Ambo A, Ouchi H, Yamamoto Y.
Bioorg Med Chem Lett (2001) 11 : 327 -329
PubMed 11212102 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.90 6.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL111028 1 6.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL111028 Kd = 125.89 nM 6.90