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Assay Detail

CHEMBL752222

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against human NMB receptor was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neuromedin-B receptor (CHEMBL3636)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PD 165929 the first high affinity non-peptide neuromedin-B (NMB) receptor selective antagonist
Eden J, Hall M, Higginbottom M, Horwell D, Howson W, Hughes J, Jordan R, Lewthwaite R, Martin K, McKnight A, O'Toole J, Pinnock R, Pritchard M, Suman-Chauhan N, Williams S
Bioorg Med Chem Lett (1996) 6 : 2617 -2622
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.20 8.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL86828 1 8.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL86828 Ki = 6.3 nM 8.20