Assay Detail
Functional
CHEMBL752707
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Compound was tested for agonist activity against opioid receptor in mouse vas deferens preparation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Irreversible blockage of opioid receptor types by ester homologues of beta-funaltrexamine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.59 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL293145 | — | — | 1 | 8.15 |
| CHEMBL301654 | — | — | 1 | 7.89 |
| CHEMBL54820 | — | — | 1 | 7.68 |
| CHEMBL293967 | — | — | 1 | 7.15 |
| CHEMBL473136 | — | — | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL293145 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL301654 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL54820 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL293967 | — | IC50 | = | 70.1 | nM | 7.15 |
| CHEMBL473136 | — | IC50 | = | 82.0 | nM | 7.09 |