Assay Detail
Functional
CHEMBL752779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity using electrically induced smooth muscle contraction of mouse vas deferens.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic delta opioid receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.70 | 8.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13470 | SNC-80 | — | 1 | 8.56 |
| CHEMBL153648 | — | — | 1 | 7.98 |
| CHEMBL150609 | — | — | 1 | 7.59 |
| CHEMBL346625 | — | — | 1 | 7.48 |
| CHEMBL542267 | — | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13470 | SNC-80 | IC50 | = | 2.73 | nM | 8.56 |
| CHEMBL153648 | — | IC50 | = | 10.5 | nM | 7.98 |
| CHEMBL150609 | — | IC50 | = | 25.7 | nM | 7.59 |
| CHEMBL346625 | — | IC50 | = | 33.1 | nM | 7.48 |
| CHEMBL542267 | — | IC50 | = | 125.0 | nM | 6.90 |