Assay Detail
Binding
CHEMBL752830
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compound was tested for inhibitory activity against neutral endopeptidase (NEP)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Highly potent and selective inhibitors of endothelin converting enzyme
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.99 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL479579 | PHOSPHORAMIDON | — | 1 | 8.38 |
| CHEMBL282660 | — | — | 1 | 6.50 |
| CHEMBL23598 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL479579 | PHOSPHORAMIDON | IC50 | = | 4.2 | nM | 8.38 |
| CHEMBL282660 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL23598 | — | IC50 | = | 800.0 | nM | 6.10 |