Assay Detail
Functional
CHEMBL752884
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Effect on synaptosomal uptake inhibition of Noradrenaline (NA)
9
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Neuroleptic activity and dopamine-uptake inhibition in 1-piperazino-3-phenylindans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.87 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1203891 | — | — | 2 | 7.72 |
| CHEMBL1204285 | — | — | 4 | 7.50 |
| CHEMBL136562 | — | — | 1 | 6.85 |
| CHEMBL1204347 | — | — | 1 | 6.82 |
| CHEMBL12628 | — | — | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1203891 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL1203891 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1204285 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL1204285 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL1204285 | — | IC50 | = | 97.0 | nM | 7.01 |
| CHEMBL136562 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL1204347 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL12628 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL1204285 | — | IC50 | = | 13000.0 | nM | 4.89 |