Assay Detail
Functional
CHEMBL753353
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro growth inhibition of Plasmodium falciparum W2
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.15 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448417 | — | — | 1 | 7.54 |
| CHEMBL289194 | — | — | 1 | 7.53 |
| CHEMBL405238 | — | — | 1 | 7.32 |
| CHEMBL386396 | — | — | 1 | 7.17 |
| CHEMBL384639 | — | — | 1 | 6.95 |
| CHEMBL46736 | — | — | 1 | 6.77 |
| CHEMBL279113 | — | — | 1 | 6.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448417 | — | IC50 | = | 29.2 | nM | 7.54 |
| CHEMBL289194 | — | IC50 | = | 29.5 | nM | 7.53 |
| CHEMBL405238 | — | IC50 | = | 47.8 | nM | 7.32 |
| CHEMBL386396 | — | IC50 | = | 67.2 | nM | 7.17 |
| CHEMBL384639 | — | IC50 | = | 111.9 | nM | 6.95 |
| CHEMBL46736 | — | IC50 | = | 170.1 | nM | 6.77 |
| CHEMBL279113 | — | IC50 | = | 179.9 | nM | 6.75 |