Assay Detail
Binding
CHEMBL753751
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Tested for inhibition constant at OT receptor of rat mammary glands
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A new series of photoactivatable and iodinatable linear vasopressin antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.31 | 9.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL441195 | — | — | 1 | 9.19 |
| CHEMBL265048 | — | — | 1 | 8.85 |
| CHEMBL412192 | — | — | 1 | 8.32 |
| CHEMBL405440 | — | — | 1 | 7.75 |
| CHEMBL424905 | — | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL441195 | — | Ki | = | 0.65 | nM | 9.19 |
| CHEMBL265048 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL412192 | — | Ki | = | 4.8 | nM | 8.32 |
| CHEMBL405440 | — | Ki | = | 18.0 | nM | 7.75 |
| CHEMBL424905 | — | Ki | = | 37.7 | nM | 7.42 |