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Assay Detail

CHEMBL753759

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Lanosterol synthase (CHEMBL3262)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Inhibition of 2,3-oxidosqualene cyclase by N-alkylpiperidines
Wannamaker M, Waid PP, Moore WR, Schatzman GL, Van Sickle WA, Wilson PK
Bioorg Med Chem Lett (1993) 3 : 1175 -1178
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.55 7.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL17168 1 7.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL17168 Ki = 28.0 nM 7.55