Assay Detail
Functional
CHEMBL753781
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonistic activity in mouse vas deferens
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Binaltorphimine-related bivalent ligands and their kappa opioid receptor antagonist selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.68 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL607010 | — | — | 1 | 7.28 |
| CHEMBL606959 | — | — | 1 | 6.77 |
| CHEMBL606960 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL607010 | — | IC50 | = | 52.0 | nM | 7.28 |
| CHEMBL606959 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL606960 | — | IC50 | = | 1000.0 | nM | 6.00 |