Assay Detail
Binding
CHEMBL753789
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Inhibition against delta-opioid receptor using [3H]DPDPE radioligand.
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Stereoisomers of N-[1-hydroxy-(2-phenylethyl)-3-methyl-4-piperidyl]- N-phenylpropanamide: synthesis, stereochemistry, analgesic activity, and opioid receptor binding characteristics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.83 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121211 | — | — | 2 | 7.05 |
| CHEMBL333410 | — | — | 1 | 6.94 |
| CHEMBL121403 | — | — | 1 | 6.70 |
| CHEMBL338510 | — | — | 1 | - |
| CHEMBL121060 | — | — | 1 | - |
| CHEMBL435380 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121211 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL333410 | — | Ki | = | 114.0 | nM | 6.94 |
| CHEMBL121403 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL121211 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL338510 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL121060 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL435380 | — | Ki | > | 10000.0 | nM | - |