Assay Detail
Functional
CHEMBL754065
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In vitro growth inhibition of Plasmodium falciparum D6
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.34 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289194 | — | — | 1 | 7.66 |
| CHEMBL405238 | — | — | 1 | 7.53 |
| CHEMBL386396 | — | — | 1 | 7.38 |
| CHEMBL384639 | — | — | 1 | 7.22 |
| CHEMBL279113 | — | — | 1 | 6.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289194 | — | IC50 | = | 21.9 | nM | 7.66 |
| CHEMBL405238 | — | IC50 | = | 29.3 | nM | 7.53 |
| CHEMBL386396 | — | IC50 | = | 41.7 | nM | 7.38 |
| CHEMBL384639 | — | IC50 | = | 59.7 | nM | 7.22 |
| CHEMBL279113 | — | IC50 | = | 123.2 | nM | 6.91 |