Assay Detail
Functional
CHEMBL754068
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro growth inhibition of Plasmodium falciparum F32
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiplasmodial activity and cytotoxicity of bis-, tris-, and tetraquinolines with linear or cyclic amino linkers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.34 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448417 | — | — | 1 | 7.75 |
| CHEMBL289194 | — | — | 1 | 7.62 |
| CHEMBL405238 | — | — | 1 | 7.46 |
| CHEMBL386396 | — | — | 1 | 7.33 |
| CHEMBL46736 | — | — | 1 | 7.19 |
| CHEMBL384639 | — | — | 1 | 7.17 |
| CHEMBL279113 | — | — | 1 | 6.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448417 | — | IC50 | = | 17.9 | nM | 7.75 |
| CHEMBL289194 | — | IC50 | = | 23.7 | nM | 7.62 |
| CHEMBL405238 | — | IC50 | = | 34.5 | nM | 7.46 |
| CHEMBL386396 | — | IC50 | = | 46.3 | nM | 7.33 |
| CHEMBL46736 | — | IC50 | = | 64.6 | nM | 7.19 |
| CHEMBL384639 | — | IC50 | = | 68.3 | nM | 7.17 |
| CHEMBL279113 | — | IC50 | = | 132.6 | nM | 6.88 |