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Assay Detail

CHEMBL754143

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Binding
Opioid receptor activity was evaluated using mouse vas deferens (MVD) assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Tissue Vas deferens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Opioid receptor (CHEMBL2095192)
Type PROTEIN FAMILY
Organism Mus musculus

Publication

Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability.
Bilsky EJ, Egleton RD, Mitchell SA, Palian MM, Davis P, Huber JD, Jones H, Yamamura HI, Janders J, Davis TP, Porreca F, Hruby VJ, Polt R.
J Med Chem (2000) 43 : 2586 -2590
PubMed 10891118 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.58 8.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1790710 1 8.57
CHEMBL70 MORPHINE 4.0 1 6.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1790710 IC50 = 2.7 nM 8.57
CHEMBL70 MORPHINE IC50 = 258.0 nM 6.59