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Assay Detail

CHEMBL754145

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for antagonistic activity against opioid receptor in mouse vas deferens
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Tissue Vas deferens
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Opioid receptor (CHEMBL2095192)
Type PROTEIN FAMILY
Organism Mus musculus

Publication

Synthesis and biological activity of analogues of beta-chlornaltrexamine and beta-funaltrexamine at opioid receptors.
Portoghese PS, Rein MD, Takemori AE.
J Med Chem (1986) 29 : 1861 -1864
PubMed 3020245 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.44 9.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL340032 DADLE 1 9.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL340032 DADLE IC50 = 0.36 nM 9.44