Assay Detail
Binding
CHEMBL754253
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibitory activity against delta opioid receptor using mouse vas deferens (MVD) assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
A topochemical approach to explain morphiceptin bioactivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.88 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2371360 | — | — | 1 | 6.70 |
| CHEMBL2371359 | — | — | 1 | 6.23 |
| CHEMBL283287 | — | — | 1 | 5.90 |
| CHEMBL267708 | — | — | 1 | 5.82 |
| CHEMBL2371339 | — | — | 1 | 5.75 |
| CHEMBL362991 | MORPHICEPTIN | — | 1 | 5.43 |
| CHEMBL2371340 | — | — | 1 | 5.32 |
| CHEMBL2371336 | — | — | 1 | - |
| CHEMBL2371361 | — | — | 1 | - |
| CHEMBL2371337 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2371360 | — | IC50 | = | 202.0 | nM | 6.70 |
| CHEMBL2371359 | — | IC50 | = | 594.0 | nM | 6.23 |
| CHEMBL283287 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL267708 | — | IC50 | = | 1508.0 | nM | 5.82 |
| CHEMBL2371339 | — | IC50 | = | 1790.0 | nM | 5.75 |
| CHEMBL362991 | MORPHICEPTIN | IC50 | = | 3690.0 | nM | 5.43 |
| CHEMBL2371340 | — | IC50 | = | 4810.0 | nM | 5.32 |
| CHEMBL2371336 | — | IC50 | = | 564800.0 | nM | - |
| CHEMBL2371361 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2371337 | — | IC50 | > | 1000000.0 | nM | - |