Assay Detail
Binding
CHEMBL754255
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Inhibitory activity against Opioid receptor delta 1 using [3H]DPDPE
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Solid phase synthesis and evaluation of Tyr-Tic-Phe-Phe(p-NHCOCH(2)Br) ([Phe(p-bromoacetamide)(4)]TIPP), a potent affinity label for delta opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.69 | 8.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3143012 | — | — | 1 | 8.27 |
| CHEMBL191751 | — | — | 1 | 7.85 |
| CHEMBL2370603 | — | — | 1 | 7.70 |
| CHEMBL2370606 | — | — | 1 | 7.44 |
| CHEMBL3143015 | — | — | 1 | 7.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3143012 | — | IC50 | = | 5.4 | nM | 8.27 |
| CHEMBL191751 | — | IC50 | = | 14.1 | nM | 7.85 |
| CHEMBL2370603 | — | IC50 | = | 19.9 | nM | 7.70 |
| CHEMBL2370606 | — | IC50 | = | 36.2 | nM | 7.44 |
| CHEMBL3143015 | — | IC50 | = | 65.0 | nM | 7.19 |