Assay Detail
Functional
CHEMBL754260
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Inhibitory concentration against delta opioid receptor of electrically induced smooth muscle contraction of mouse vas deferens
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Cyclic enkephalin analogs with exceptional potency at peripheral delta opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 9.90 | 10.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL339320 | — | — | 1 | 10.80 |
| CHEMBL2372314 | — | — | 1 | 10.55 |
| CHEMBL2372327 | — | — | 1 | 10.55 |
| CHEMBL2372328 | — | — | 1 | 10.12 |
| CHEMBL317956 | DELTORPHIN C | — | 1 | 9.80 |
| CHEMBL2372310 | — | — | 1 | 9.52 |
| CHEMBL2372329 | — | — | 1 | 9.49 |
| CHEMBL31421 | — | — | 1 | 8.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL339320 | — | IC50 | = | 0.016 | nM | 10.80 |
| CHEMBL2372314 | — | IC50 | = | 0.028 | nM | 10.55 |
| CHEMBL2372327 | — | IC50 | = | 0.028 | nM | 10.55 |
| CHEMBL2372328 | — | IC50 | = | 0.076 | nM | 10.12 |
| CHEMBL317956 | DELTORPHIN C | IC50 | = | 0.16 | nM | 9.80 |
| CHEMBL2372310 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL2372329 | — | IC50 | = | 0.32 | nM | 9.49 |
| CHEMBL31421 | — | IC50 | = | 4.1 | nM | 8.39 |