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Assay Detail

CHEMBL754348

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Equilibrium dissociation constant at cloned rat Neurotensin receptor (NT) receptor expressed in CHO-K1 cells; 0.3-0.7 uM
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO-K1
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neurotensin receptor type 1 (CHEMBL3027)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis of partially non-peptidic neurotensin mimetics
Dood DS, Kozikowski AP, Cusack B, Richelson E
Bioorg Med Chem Lett (1994) 4 : 1241 -1246
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 3 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL21521 1 6.52
CHEMBL21448 1 6.52
CHEMBL21892 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL21521 Kd = 300.0 nM 6.52
CHEMBL21448 Kd = 300.0 nM 6.52
CHEMBL21892 Kd = 300.0 nM 6.52