Assay Detail
Binding
CHEMBL754407
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Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaCl
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Preparation and analgesic properties of amino acid derivatives of (-)-5,9 alpha-diethyl-2'-hydroxybenzomorphan.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.71 | 7.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL26232 | — | — | 1 | 7.81 |
| CHEMBL13786 | — | — | 1 | 7.75 |
| CHEMBL286206 | — | — | 1 | 6.54 |
| CHEMBL282347 | — | — | 1 | 6.52 |
| CHEMBL1159833 | — | — | 1 | 5.82 |
| CHEMBL25778 | — | — | 2 | 5.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL26232 | — | IC50 | = | 15.5 | nM | 7.81 |
| CHEMBL13786 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL286206 | — | IC50 | = | 287.0 | nM | 6.54 |
| CHEMBL282347 | — | IC50 | = | 301.0 | nM | 6.52 |
| CHEMBL1159833 | — | IC50 | = | 1503.0 | nM | 5.82 |
| CHEMBL25778 | — | IC50 | = | 1540.0 | nM | 5.81 |
| CHEMBL25778 | — | IC50 | > | 10000.0 | nM | - |