Assay Detail
Binding
CHEMBL754615
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Binding affinity towards Opioid receptor kappa 1 in guinea pig brain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Arylacetamide-derived fluorescent probes: synthesis, biological evaluation, and direct fluorescent labeling of kappa opioid receptors in mouse microglial cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.28 | 9.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1907788 | — | — | 1 | 9.51 |
| CHEMBL1907787 | — | — | 1 | 9.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1907788 | — | Ki | = | 0.31 | nM | 9.51 |
| CHEMBL1907787 | — | Ki | = | 0.91 | nM | 9.04 |