Assay Detail
Binding
CHEMBL754964
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Compound was tested for its binding affinity against opioid receptor mu using [3H]DAGO as radioligand.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Stereospecificity of amino acid side chains in deltorphin defines binding to opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.40 | 7.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20999 | — | — | 1 | 7.49 |
| CHEMBL20956 | — | — | 1 | 7.36 |
| CHEMBL20775 | DELTORPHIN A | — | 1 | 6.46 |
| CHEMBL277249 | — | — | 1 | 6.31 |
| CHEMBL278542 | — | — | 1 | 5.63 |
| CHEMBL20817 | — | — | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20999 | — | Ki | = | 32.6 | nM | 7.49 |
| CHEMBL20956 | — | Ki | = | 43.7 | nM | 7.36 |
| CHEMBL20775 | DELTORPHIN A | Ki | = | 343.8 | nM | 6.46 |
| CHEMBL277249 | — | Ki | = | 492.0 | nM | 6.31 |
| CHEMBL278542 | — | Ki | = | 2351.0 | nM | 5.63 |
| CHEMBL20817 | — | Ki | = | 7410.0 | nM | 5.13 |