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Assay Detail

CHEMBL755156

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Functional
Agonistic activity towards Opioid receptors in the guinea pig ileum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Ileum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Mu-type opioid receptor (CHEMBL4354)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Structure-activity relationships of dynorphin a analogues modified in the address sequence.
Schlechtingen G, DeHaven RN, Daubert JD, Cassel JA, Chung NN, Schiller PW, Taulane JP, Goodman M.
J Med Chem (2003) 46 : 2104 -2109
PubMed 12747782 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.62 8.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405190 1 8.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405190 IC50 = 2.38 nM 8.62