Assay Detail
Functional
CHEMBL755220
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Functional biological activity for Opioid receptor delta 1 was determined in vitro, on mouse vas deferens (MVD).
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Vas deferens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Helix-inducing alpha-aminoisobutyric acid in opioid mimetic deltorphin C analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.40 | 9.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL420606 | — | — | 1 | 9.44 |
| CHEMBL317956 | DELTORPHIN C | — | 1 | 9.34 |
| CHEMBL315225 | — | — | 1 | 8.84 |
| CHEMBL315603 | — | — | 1 | 7.24 |
| CHEMBL441889 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL420606 | — | IC50 | = | 0.36 | nM | 9.44 |
| CHEMBL317956 | DELTORPHIN C | IC50 | = | 0.46 | nM | 9.34 |
| CHEMBL315225 | — | IC50 | = | 1.44 | nM | 8.84 |
| CHEMBL315603 | — | IC50 | = | 57.3 | nM | 7.24 |
| CHEMBL441889 | — | IC50 | = | 70.0 | nM | 7.16 |