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Assay Detail

CHEMBL755354

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for Inhibition of binding of [3H]- DAMGO to Rat brain Opioid receptor mu 1 binding site
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mu-type opioid receptor (CHEMBL270)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity.
Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC.
J Med Chem (1996) 39 : 2081 -2086
PubMed 8642567 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL38791 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL38791 IC50 = 21.1 nM 7.68