Assay Detail
Functional
CHEMBL755996
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Compound was evaluated for cytotoxicity against human ovarian cancer cell CHI
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Cancer cell lines |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.55 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292475 | — | — | 1 | 6.75 |
| CHEMBL292124 | — | — | 1 | 5.08 |
| CHEMBL224248 | QUINDOLINE | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292475 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL292124 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL224248 | QUINDOLINE | IC50 | = | 15500.0 | nM | 4.81 |